Tetramethyl Ammonium Fluoride Tetrahydrate CAS NO. 17787-40-5/373-68-2, simply called TMAF or TMAF Tetrahydrate. White Crystal. Easily hygroscopic, soluble in Water, Alcohol and Chloroform. Easy to melt when temperature over 40℃. Made from Tetramethyl Ammonium Hydroxide and hydrofluoric acid via neutralization reaction. Mainly used as fluorination catalysts and fluorinating agents.
Tetramethyl Ammonium Fluoride Tetrahydrate CAS NO. 17787-40-5/373-68-2 TMAF
Description
- CAS NO.: 17787-40-5/373-68-2
- Molecular Formula: C₄H₁₂NF·4H₂O
- Molecular Weight: 165.2
- Purity (Content): 98% min. (including crystal water)
- Appearance: White Crystal
- Package: 20KG/drum with pallets
Details
Tetramethyl Ammonium Fluoride Tetrahydrate CAS NO. 17787-40-5/373-68-2, simply called TMAF or TMAF Tetrahydrate. High purity. White crystals. Special Quaternary Ammonium Salts with special anion. Easily hygroscopic, soluble in Water, Alcohol, and Chloroform. Easy to melt when temperature over 40℃.
Specifications
- Tetramethyl Ammonium Fluoride Tetrahydrate
| Appearance | White Solid |
| Assay(by Titration) | 98% min. (including crystal water) |
| Melting point | 39 ~ 42℃ |
| Moisture | 2% max. |
Application
- TMAF commonly used as a weak base and fluoride ion source in various organic reactions, including nucleophilic substitution, functional group deprotection and ring opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a multifunctional reagent in synthetic chemistry.
- Used as a fluorinating agent in medicinal chemistry for the preparation of radioactive tracers and protein modifications in biochemistry. The tetrahydrate form of TMAF is more stable and easier to handle than its anhydrous form.
- Used as phase transfer catalysts in organic synthesis chemical reactions.
- Used as cleaning agent in electrochemistry.
- Used as selective fluorination catalysts and fluorinating agents, silane protecting group removal agents in chemical synthesis.
Package
| TMAF Tetrahydrate | 20KG/drum, 18 drums/pallet, total 7.2mt in 20’FCL or 14.4mt in 40’FCL |
FAQ
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AWe don’t have MOQ for mostly regular products. We can ship 500g, 1KG or 5KG by courier or by air for testing. And for more quantities, we can ship by sea in LCL or FCL. For some special customized products, we have MOQ around 100KG to 1MT.
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AYes, we can support VQ documentation and necessary paperwork. We are regular supplier for many heavy customers in China or overseas. We have rich experience for documentation works to meet customers’ company policies.
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AYes, we can arrange factory visiting or factory audit. Before the shipment, we can also arrange testing witness in our lab for our products.

